UnScramble this Word: i s a p l e o r?

Questions

In 1809 Alfred Lord---------- , poet laureate of England, born. ?

In 1825 ---------- gains independence from Spain (National Day). ?

In 1825 Bolivia gains independence from ---------- (National Day). ?

In 1881 Sir ---------- Fleming, cashed in on penicillin (Nobel 1954), born. ?

In 1881 Sir Alexander---------- , cashed in on penicillin (Nobel 1954), born. ?