UnScramble this Word: k l i n o i s s?

Questions

What is close to Londons Isle of Dogs which leads it to have street names such as Cuba Street,Tobago Street etc?

Who reached the summit of Everest with Hillary in 1953?

What reduction is indicated when a measurement is prefixd by the word pico?

What disaster hit Ireland between 1845 & 1849?

Who are Yum-Yum and Nanki-Poo?